Homes have been flooded and rescue teams are trying to help vulnerable residents in Wheeler Street, Aston.
Cars were left partially underwater and stretches of road have been ruined after the pipe burst on Saturday.
The damaged pipe is 30in (76cm) in diameter.
There have been no reported injuries so far but up to 100 homes are affected, West Midlands Fire and Rescue said.
The service was called just before 8am on Saturday to tackle the problem.
Our crews arrived less than five minutes later and were confronted with large amounts of water across the road and affecting a significant number of properties, said Mark Hudson, a press officer for the service.
People should avoid the area as crews work to make the area safe, the service urged.
Much of the water has drained away but the severe damage to the road still poses a risk to the public.
Severn Trent Water said it was working hard to restore supplies for all homes by Saturday afternoon as water levels dropped from around midday.
Given that the burst pipe is 30in (76cm) in diameter, it might take us a little time to get everyone back on, and people might come back on in stages rather than all at once, but we’ll be working hard to achieve that, a spokesperson said.
They added In the meantime, we’re delivering bottled water to our vulnerable customers.
We know how difficult it is to have no water and we’re sorry for the inconvenience this may be causing.
News Source SkyNews