A new gene has been discovered that makes people crave coffee .
Some people can’t get through the day without their regular caffeine hit, while for others just one can suffice.
Now Scottish, Italian and Dutch scientists have found those with a particular gene drink on average one cup less than those without it because caffeine stays in the body for longer.
They identified the a DNA variation in a gene called PDSS2 and suggested it reduce the ability of cells to breakdown caffeine.
As a result they do not need to drink as much coffee to get the same caffeine hit.
The study adds to previous research that identified genes linked to coffee habits and shed new light on the biological mechanisms of caffeine metabolism.
It involved looking at genetic information from 370 people living in a small village in south Italy and 843 people from six villages in north-east Italy.
They all completed surveys that included a question about how many cups of coffee they drank each day.
People with the DNA variation in PDSS2 tended to consume fewer cups of coffee than people without the variation – the equivalent to around one fewer cup of coffee per day on average.
It was replicated in 1,731 Dutch with similar results but the number of cups of coffee consumed was slightly lower.
This could be because in Italy people tend to drink smaller cups such as espresso whereas in the Netherlands the preference is towards larger cups that contain more caffeine overall.
Dr Nicola Pirastu, a Chancellor’s Fellow at the University of Edinburgh ‘s Usher Institute, said: “The results of our study add to existing research suggesting that our drive to drink coffee may be embedded in our genes.
“We need to do larger studies to confirm the discovery and also to clarify the biological link between PDSS2 and coffee consumption.”
News Source MirrorNews